{"id":7529589375127,"title":"Jarrow Formulas Glutathione Reduced 500 mg - 60 Veggie Caps - Pharmaceutical Grade Glutathione - Intracellular Antioxidant - Bolsters Regeneration of Vitamin C \u0026 E Levels in Body - 60 Servings 60 Count (Pack of 1)","handle":"jarrow-formulas-glutathione-reduced-500-mg-60-veggie-caps-pharmaceutical-grade-glutathione-intracellular-antioxidant-bolsters-regeneration-of-vitamin-c-e-levels-in-body-60-servings-60-count-pack-of-1","description":"\u003ch3\u003eJarrow Formulas Glutathione Reduced 500 mg - 60 Veggie Caps - Pharmaceutical Grade Glutathione - Intracellular Antioxidant - Bolsters Regeneration of Vitamin C \u0026amp; E Levels in Body - 60 Servings\u003c\/h3\u003e\n\u003cp id=\"b\"\u003eJarrow Formulas Glutathione Reduced delivers 500 mg of\nglutathione per capsule. Glutathione is the most abundant intracellular thiol\n(i.e., a compound with a sulfhydryl group) and low molecular weight tripeptide\nfound in living cells. Tripeptide includes glycine, cysteine, and glutamate.\nThe antioxidant functions of glutathione include recycling vitamin E and C and\nserving as an antioxidant in all types of tissues. A low ratio of reduced vs\noxidized glutathione is used as a measure of cellular toxicity. \nJarrow Formulas Reduced Glutathione, 500mg, 60 CapsulesAt a Glance:Glutathione\nis a sulfur-containing, tri-peptide that the body utilizes to balance the\nredox potential of cells Regulates detoxification when in reduced formIdeal\nfor those interested in a naturally occurring antioxidant and detoxification\nagent that can also help bolster vitamin C \u0026amp; E levels in the\nbodyPharmaceutical grade, non-oxidized form Glutathione is a tri-peptide that\nthe body utilizes to balance the redox potential of cells. Produced in a\npharmaceutical grade, non-oxidized form. View larger. Glutathione (GSH) is a\ntri-peptide composed of the amino acids glycine, cysteine, and glutamate. As\none of the primary protective molecules in the body it is found, inside and\noutside of cells, in all tissues and body fluids. GSH is most highly\nconcentrated in the liver, spleen, kidney, eye-lens, erythrocytes, and\nleukocytes. Higher glutathione status and\/or dietary intakes have been\ncorrelated with cardiovascular, oral and eye health, as well as increased\nvitality with aging. The best food sources of glutathione are fresh fruits\nand vegetables and newly prepared meats. Since most methods of food processing\ndestroy glutathione, the excessive intake of processed foods may be leading to\nmodern diets that are often devoid of glutathione. Studies evaluating dietary\nintake from food have found wide variations amongst individuals: 3-250 mg\/day\n(mean: 35 mg\/day). Additionally, body-stores tend to decrease with age and\neven fluctuate throughout the day.Good By Mouth Since GSH is a peptide, many\nassume that it is completely digested by enzymes in the intestines. Further\nfueling this assumption, early studies did not find an appreciable increase in\nplasma levels after GSH ingestion. However, it now appears that GSH's uncommon\nlinkage amongst the glutamate side-chain and the cysteine residue makes GSH\npartially resistant to common peptide cleavage enzymes. This not only impacts\nits digestion, but also its regulation inside the body. Numerous studies have\nnow demonstrated that oral glutathione is bioavailable and that blood levels\nmay stay relatively constant even as tissue levels rise. Oral glutathione\nfeeds bodily tissues via three routes 1) absorption intact in the intestines\nfollowed by tissue uptake from blood, 2) degradation to its constituent amino\nacids in the GI tract, cellular absorption, then intracellular GSH re-\nsynthesis, and 3) terminal passage into cells that line the GI tract. The\navailability of L-cysteine is the bottleneck for glutathione synthesis in the\nbody, since cysteine is the least prevalent of glutathione's three constituent\namino acids in the diet. This is one reason N-acetylcysteine (NAC) is also\nused to support glutathione levels. Overall, there are about 15 grams of GSH\nin the body, of which roughly four grams can be found in the liver.RedOx \u0026amp;\nDetox GSH is the major endogenous antioxidant produced by the body, possessing\na substantial reduction-oxidation (i.e. \"redox\") potential. Thus it can\nparticipate both directly and indirectly in the neutralization of free\nradicals and reactive oxygen species. It also helps maintain levels of\nexogenous antioxidants, such as vitamins C and E, in active forms. And of\ncourse, GSH is a cofactor for the enzyme glutathione peroxidase, which\nprimarily protects the body from oxidative damage. GSH is added to lipophilic\ntoxins, waste and xenobiotics in the liver during phase-2 detoxification to\nmake them water-soluble and allow excretion from the body. As one example, GSH\nis necessary for the detoxification of methylglyoxal, a toxin produced as a\nby-product of human metabolism and thought to be a source of advanced\nglycation end-products (AGEs). GSH is also necessary to avoid acetaminophen\ntoxicity. In fact, GSH levels are often intentionally bolstered in cases of\noverdose. GSH keeps the acetaminophen metabolite NAPQI from binding to thiol\ngroups of cellular proteins and causing cell-death.What's Your G-Ratio? The\nratio of reduced glutathione to oxidized glutathione within cells is often\nused as a measure of cellular toxicity. In healthy cells and tissue, more than\n90 percent of the total glutathione pool is in the reduced form (GSH) and less\nthan 10 percent exists in the disulfide form (GSSG). An increased GSSG-to-GSH\nratio is considered indicative of oxidative stress and sometimes tissue\ndysfunction. Besides a poor diet, other lifestyle factors like smoking\ncigarettes, excessively consuming alcohol and chronically taking medications\ncan alter the GSSG-to-GSH ratio. If your G-ratio needs work, try Jarrow\nFORMULAS Glutathione Reduced.Contains: No wheat, no gluten, no soybeans, no\ndairy, no egg, no fish\/shellfish, no peanuts\/tree nuts.Usage Directions: Take\n1 capsule per day with a meal or as directed by your qualified health care\nconsultant.About Jarrow Formulas Jarrow Formulas' complete line of over 350\nnutritional products includes vitamins, minerals, probiotics, standardized\nherbal concentrates, amino acids, enzymes and enteral nutrition products.\nCustomers can be assured of purity, value and potency when choosing these\nproducts.What's in the Box Jarrow Formulas Reduced Glutathione, 500mg, 60\nCapsules.Other Products from Jarrow Formulas\u003c\/p\u003e \n\n\u003ch3\u003eProduct Features\u003c\/h3\u003e\n \u003cul class=\"a\"\u003e\n \u003cli\u003ePharmaceutical Grade Glutathione: Glutathione is the most abundant intracellular thiol (ie, a compound with a sulfhydryl group) and low molecular weight tripeptide found in living cells; Tripeptide includes glycine, cysteine and glutamate\u003c\/li\u003e\n \u003cli\u003eIntracellular Antioxidant: The antioxidant functions of glutathione include recycling vitamin E and C and serving as an antioxidant in all types of tissues; A low ratio of reduced vs oxidized glutathione is used as a measure of cellular toxicity\u003c\/li\u003e\n \u003cli\u003eVeggie Capsules: Each veggie capsule delivers 500 mg of glutathione; Take one capsule per day with a meal or as directed by your qualified healthcare professional\u003c\/li\u003e\n \u003cli\u003eSuperior Nutrition and Formulation: The goal of Jarrow Formulas is to promote optimal health with high-quality, effective, affordable, and superior formulation of dietary supplements; Our customers can be assured of purity, value, and potency\u003c\/li\u003e\n \u003c\/ul\u003e\n","published_at":"2022-04-17T19:53:14+10:00","created_at":"2022-04-17T19:53:26+10:00","vendor":"Jarrow Formulas","type":"Combinations","tags":["babyhousehold"],"price":13200,"price_min":13200,"price_max":13200,"available":true,"price_varies":false,"compare_at_price":null,"compare_at_price_min":0,"compare_at_price_max":0,"compare_at_price_varies":false,"variants":[{"id":41985650622615,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"B0013OULOM","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Jarrow Formulas Glutathione Reduced 500 mg - 60 Veggie Caps - Pharmaceutical Grade Glutathione - Intracellular Antioxidant - Bolsters Regeneration of Vitamin C \u0026 E Levels in Body - 60 Servings 60 Count (Pack of 1)","public_title":null,"options":["Default Title"],"price":13200,"weight":59,"compare_at_price":null,"inventory_management":null,"barcode":"790011150398","requires_selling_plan":false,"selling_plan_allocations":[]}],"images":["\/\/newnestshop.com\/cdn\/shop\/products\/B0013OULOM.jpg?v=1650235589","\/\/newnestshop.com\/cdn\/shop\/products\/71N0RBiOGzL.jpg?v=1650189206","\/\/newnestshop.com\/cdn\/shop\/products\/81zzpAHjo4L.jpg?v=1650189206","\/\/newnestshop.com\/cdn\/shop\/products\/8167SgIWuQL.jpg?v=1650189206","\/\/newnestshop.com\/cdn\/shop\/products\/41P5Gcm6xDL.jpg?v=1650189206","\/\/newnestshop.com\/cdn\/shop\/products\/71tF--0xzwL.jpg?v=1650189206","\/\/newnestshop.com\/cdn\/shop\/products\/81gXfiW4ydL.jpg?v=1650189206","\/\/newnestshop.com\/cdn\/shop\/products\/81TzsgL2iOL_c057fa28-2b83-4caa-9641-7723ccda2ff4.jpg?v=1650189206","\/\/newnestshop.com\/cdn\/shop\/products\/81YRELG-M_L_e995d9af-0ec6-4d0a-b7fc-303a0174dcf0.jpg?v=1650189206","\/\/newnestshop.com\/cdn\/shop\/products\/31pJt15CQLL.jpg?v=1650189206","\/\/newnestshop.com\/cdn\/shop\/products\/71oDuWiW_LL.jpg?v=1650189206"],"featured_image":"\/\/newnestshop.com\/cdn\/shop\/products\/B0013OULOM.jpg?v=1650235589","options":["Title"],"media":[{"alt":"Jarrow Formulas Glutathione Reduced 500 mg - 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Glutathione is the most abundant intracellular thiol\n(i.e., a compound with a sulfhydryl group) and low molecular weight tripeptide\nfound in living cells. Tripeptide includes glycine, cysteine, and glutamate.\nThe antioxidant functions of glutathione include recycling vitamin E and C and\nserving as an antioxidant in all types of tissues. A low ratio of reduced vs\noxidized glutathione is used as a measure of cellular toxicity. \nJarrow Formulas Reduced Glutathione, 500mg, 60 CapsulesAt a Glance:Glutathione\nis a sulfur-containing, tri-peptide that the body utilizes to balance the\nredox potential of cells Regulates detoxification when in reduced formIdeal\nfor those interested in a naturally occurring antioxidant and detoxification\nagent that can also help bolster vitamin C \u0026amp; E levels in the\nbodyPharmaceutical grade, non-oxidized form Glutathione is a tri-peptide that\nthe body utilizes to balance the redox potential of cells. Produced in a\npharmaceutical grade, non-oxidized form. View larger. Glutathione (GSH) is a\ntri-peptide composed of the amino acids glycine, cysteine, and glutamate. As\none of the primary protective molecules in the body it is found, inside and\noutside of cells, in all tissues and body fluids. GSH is most highly\nconcentrated in the liver, spleen, kidney, eye-lens, erythrocytes, and\nleukocytes. Higher glutathione status and\/or dietary intakes have been\ncorrelated with cardiovascular, oral and eye health, as well as increased\nvitality with aging. The best food sources of glutathione are fresh fruits\nand vegetables and newly prepared meats. Since most methods of food processing\ndestroy glutathione, the excessive intake of processed foods may be leading to\nmodern diets that are often devoid of glutathione. Studies evaluating dietary\nintake from food have found wide variations amongst individuals: 3-250 mg\/day\n(mean: 35 mg\/day). Additionally, body-stores tend to decrease with age and\neven fluctuate throughout the day.Good By Mouth Since GSH is a peptide, many\nassume that it is completely digested by enzymes in the intestines. Further\nfueling this assumption, early studies did not find an appreciable increase in\nplasma levels after GSH ingestion. However, it now appears that GSH's uncommon\nlinkage amongst the glutamate side-chain and the cysteine residue makes GSH\npartially resistant to common peptide cleavage enzymes. This not only impacts\nits digestion, but also its regulation inside the body. Numerous studies have\nnow demonstrated that oral glutathione is bioavailable and that blood levels\nmay stay relatively constant even as tissue levels rise. Oral glutathione\nfeeds bodily tissues via three routes 1) absorption intact in the intestines\nfollowed by tissue uptake from blood, 2) degradation to its constituent amino\nacids in the GI tract, cellular absorption, then intracellular GSH re-\nsynthesis, and 3) terminal passage into cells that line the GI tract. The\navailability of L-cysteine is the bottleneck for glutathione synthesis in the\nbody, since cysteine is the least prevalent of glutathione's three constituent\namino acids in the diet. This is one reason N-acetylcysteine (NAC) is also\nused to support glutathione levels. Overall, there are about 15 grams of GSH\nin the body, of which roughly four grams can be found in the liver.RedOx \u0026amp;\nDetox GSH is the major endogenous antioxidant produced by the body, possessing\na substantial reduction-oxidation (i.e. \"redox\") potential. Thus it can\nparticipate both directly and indirectly in the neutralization of free\nradicals and reactive oxygen species. It also helps maintain levels of\nexogenous antioxidants, such as vitamins C and E, in active forms. And of\ncourse, GSH is a cofactor for the enzyme glutathione peroxidase, which\nprimarily protects the body from oxidative damage. GSH is added to lipophilic\ntoxins, waste and xenobiotics in the liver during phase-2 detoxification to\nmake them water-soluble and allow excretion from the body. As one example, GSH\nis necessary for the detoxification of methylglyoxal, a toxin produced as a\nby-product of human metabolism and thought to be a source of advanced\nglycation end-products (AGEs). GSH is also necessary to avoid acetaminophen\ntoxicity. In fact, GSH levels are often intentionally bolstered in cases of\noverdose. GSH keeps the acetaminophen metabolite NAPQI from binding to thiol\ngroups of cellular proteins and causing cell-death.What's Your G-Ratio? The\nratio of reduced glutathione to oxidized glutathione within cells is often\nused as a measure of cellular toxicity. In healthy cells and tissue, more than\n90 percent of the total glutathione pool is in the reduced form (GSH) and less\nthan 10 percent exists in the disulfide form (GSSG). An increased GSSG-to-GSH\nratio is considered indicative of oxidative stress and sometimes tissue\ndysfunction. Besides a poor diet, other lifestyle factors like smoking\ncigarettes, excessively consuming alcohol and chronically taking medications\ncan alter the GSSG-to-GSH ratio. If your G-ratio needs work, try Jarrow\nFORMULAS Glutathione Reduced.Contains: No wheat, no gluten, no soybeans, no\ndairy, no egg, no fish\/shellfish, no peanuts\/tree nuts.Usage Directions: Take\n1 capsule per day with a meal or as directed by your qualified health care\nconsultant.About Jarrow Formulas Jarrow Formulas' complete line of over 350\nnutritional products includes vitamins, minerals, probiotics, standardized\nherbal concentrates, amino acids, enzymes and enteral nutrition products.\nCustomers can be assured of purity, value and potency when choosing these\nproducts.What's in the Box Jarrow Formulas Reduced Glutathione, 500mg, 60\nCapsules.Other Products from Jarrow Formulas\u003c\/p\u003e \n\n\u003ch3\u003eProduct Features\u003c\/h3\u003e\n \u003cul class=\"a\"\u003e\n \u003cli\u003ePharmaceutical Grade Glutathione: Glutathione is the most abundant intracellular thiol (ie, a compound with a sulfhydryl group) and low molecular weight tripeptide found in living cells; Tripeptide includes glycine, cysteine and glutamate\u003c\/li\u003e\n \u003cli\u003eIntracellular Antioxidant: The antioxidant functions of glutathione include recycling vitamin E and C and serving as an antioxidant in all types of tissues; A low ratio of reduced vs oxidized glutathione is used as a measure of cellular toxicity\u003c\/li\u003e\n \u003cli\u003eVeggie Capsules: Each veggie capsule delivers 500 mg of glutathione; Take one capsule per day with a meal or as directed by your qualified healthcare professional\u003c\/li\u003e\n \u003cli\u003eSuperior Nutrition and Formulation: The goal of Jarrow Formulas is to promote optimal health with high-quality, effective, affordable, and superior formulation of dietary supplements; Our customers can be assured of purity, value, and potency\u003c\/li\u003e\n \u003c\/ul\u003e\n"}